Analysis of human growth hormone gene 5' sequences in isolated growth hormone deficiency patients.
نویسندگان
چکیده
Human growth hormone (hGH) gene deletion (6.7 to 7.6 kb) is one of the causes of isolated growth hormone deficiency (IGHD), named IGHD IA. IGHD IA, however, only accounts for about 10% of the total IGHD patients. Most IGHD is caused by unknown mechanisms. Here, hGH gene 5' sequences in three IGHD patients without hGH gene deletion were analysed to see if there was any mutation hindering the expression of the hGH gene.
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ورودعنوان ژورنال:
- Journal of medical genetics
دوره 31 1 شماره
صفحات -
تاریخ انتشار 1994